Tissue Factor Expression on Platelet Surface during Preparation and Storage of Platelet Concentrates | Zendy

Alfonso Vignoli | Zendy; Cinzia Giaccherini | Zendy; Marina Marchetti | Zendy; Cristina Verzeroli | Zendy; Chiara Gargantini | Zendy; Luca Da Prada | Zendy; Barbara Giussani | Zendy; Anna Falanga | Zendy

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Tissue Factor Expression on Platelet Surface during Preparation and Storage of Platelet Concentrates

Author(s) -

Alfonso Vignoli,

Cinzia Giaccherini,

Marina Marchetti,

Cristina Verzeroli,

Chiara Gargantini,

Luca Da Prada,

Barbara Giussani,

Anna Falanga

Publication year - 2013

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000350330

Subject(s) - platelet , tissue factor , buffy coat , coagulation , platelet activation , whole blood , andrology , chemistry , immunology , flow cytometry , medicine

Tissue factor (TF), the main activator of blood coagulation, is expressed on platelet surface and, together with procoagulant phospholipids, contributes to the global coagulation potential of these blood components. The present study evaluated, for the first time, the expression of TF on platelet surface during preparation and storage of platelet concentrates (PC) for transfusional use.

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