Whole Body Irradiation Induces Cutaneous Dendritic Cells Depletion via NF-κB Activation
Author(s) -
Yanyong Yang,
Jianguo Cui,
Fu Gao,
Bailong Li,
Cong Liu,
Pei Zhang,
Yijuan Huang,
Wen Liu,
Hu Liu,
Jianming Cai
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000350136
Subject(s) - ccl19 , chemokine , chemistry , c c chemokine receptor type 7 , lymph node , western blot , immune system , dendritic cell , flow cytometry , microbiology and biotechnology , cancer research , biology , immunology , chemokine receptor , biochemistry , gene
Effect of ionizing radiation on cutaneous dendritic cells (cDC) is critical to its influence on immune status of the skin, which plays an important role in the progression and recovery of radiation skin sickness. This study was to study the influence of whole body irradiation (WBI) on the cDC.
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