Coculture of Embryonic Ventricular Myocytes and Mouse Embryonic Stem Cell Enhance Intercellular Signaling by Upregulation of Connexin43 | Zendy

Hui Li | Zendy; Ming Tang | Zendy; Huamin Liang | Zendy; Yuting Li | Zendy; Jian Wang | Zendy; Yuanlong Song | Zendy; Yunjie Zheng | Zendy; Jiaoya Xi | Zendy; Jinxia Zhang | Zendy; Jürgen Hescheler | Zendy; Minjie Zhu | Zendy

Open Access

Coculture of Embryonic Ventricular Myocytes and Mouse Embryonic Stem Cell Enhance Intercellular Signaling by Upregulation of Connexin43

Author(s) -

Hui Li,

Ming Tang,

Huamin Liang,

Yuting Li,

Jian Wang,

Yuanlong Song,

Yunjie Zheng,

Jiaoya Xi,

Jinxia Zhang,

Jürgen Hescheler,

Minjie Zhu

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000350124

Subject(s) - embryonic stem cell , microbiology and biotechnology , stem cell , myocyte , downregulation and upregulation , embryoid body , transplantation , gap junction , biology , intracellular , stem cell therapy , embryonic heart , adult stem cell , immunology , medicine , genetics , gene

Stem cell therapy has been proposed as a potential treatment strategy for ischemic cardiomyopathy in recent years. A variety of stem cells or stem cell-derived cells can potentially be used for transplantation. Despite improved cardiac function after treatment, one of the major problems is the poor integration between host and donor cells which can lead to post-transplantation arrhythmia and poor long-term outcome.

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