Evidence for the Formation of Symmetric and Asymmetric DLPC-DAPC Lipid Bilayer Domains | Zendy

Markus Ritter | Zendy; Sabine Schmidt | Zendy; Martin Jakab | Zendy; Markus Paulmichl | Zendy; Robert M. Henderson | Zendy

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Evidence for the Formation of Symmetric and Asymmetric DLPC-DAPC Lipid Bilayer Domains

Author(s) -

Markus Ritter,

Sabine Schmidt,

Martin Jakab,

Markus Paulmichl,

Robert M. Henderson

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000350122

Subject(s) - lipid bilayer , chemistry , bilayer , crystallography , lipid raft , molecular dynamics , phosphatidylcholine , atomic force microscopy , phospholipid , membrane , materials science , nanotechnology , computational chemistry , biochemistry

We investigated if mixtures of the phosphatidylcholine (PC) lipids 1,2-dilauroyl-sn-glycero-3-phosphocholine (C12:0 PC; DLPC) and 1,2-diarachidoyl-sn-glycero-3-phosphocholine (C20:0 PC; DAPC), which differ by eight methylene groups in acyl chain length, lead to the spontaneous formation of distinct lipid rafts and asymmetric bilayers.

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