Down-Regulation of TRPM8 in Pulmonary Arteries of Pulmonary Hypertensive Rats | Zendy

Xiao-Ru Liu | Zendy; Qing Liu | Zendy; Gai-Ying Chen | Zendy; Ying Hu | Zendy; James S.K. Sham | Zendy; MoJun Lin | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Down-Regulation of TRPM8 in Pulmonary Arteries of Pulmonary Hypertensive Rats

Author(s) -

Xiao-Ru Liu,

Qing Liu,

Gai-Ying Chen,

Ying Hu,

James S.K. Sham,

MoJun Lin

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000350107

Subject(s) - phenylephrine , downregulation and upregulation , transient receptor potential channel , right ventricular hypertrophy , trpm8 , endocrinology , medicine , pulmonary hypertension , pulmonary artery , agonist , vascular smooth muscle , pharmacology , chemistry , receptor , blood pressure , smooth muscle , biochemistry , trpv1 , gene

Pulmonary hypertension (PH) is characterized by profound vascular remodeling and alterations in Ca(2+) homeostasis in pulmonary arterial smooth muscle cells (PASMCs). Multiple transient receptor potential melastatin-related (TRPM) subtypes have been identified in vascular tissue. However, the changes in the expression and function of TRPM channels in pulmonary hypertension have not been characterized in detail.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research