Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues | Zendy

Haider Raza | Zendy; Annie John | Zendy; Abderrahim Nemmar | Zendy

Open Access

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

Author(s) -

Haider Raza,

Annie John,

Abderrahim Nemmar

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000350087

Subject(s) - chemistry , tumor necrosis factor alpha , reactive oxygen species , p38 mitogen activated protein kinases , nadph oxidase , protein kinase b , oxidative stress , inflammation , nox4 , phosphorylation , protein kinase a , endocrinology , medicine , immunology , biochemistry , biology

The components of cigarette smoke (CS) have been implicated in the development of cancer as well as in cardiopulmonary diseases. We have previously reported increased oxidative stress in rat tissues induced by tobacco-specific toxins nicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Recently, we have also shown increased oxidative stress and associated inflammatory responses in various tissues after exposure to cigarette smoke.

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