Amphipaths Differentially Modulate Membrane Surface Deformation in Rat Peritoneal Mast Cells During Exocytosis | Zendy

Itsuro Kazama | Zendy; Yoshio Maruyama | Zendy; Sara Takahashi | Zendy; Takashi Kokumai | Zendy

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Amphipaths Differentially Modulate Membrane Surface Deformation in Rat Peritoneal Mast Cells During Exocytosis

Author(s) -

Itsuro Kazama,

Yoshio Maruyama,

Sara Takahashi,

Takashi Kokumai

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000350079

Subject(s) - exocytosis , chlorpromazine , biophysics , microbiology and biotechnology , membrane , chemistry , cell membrane , vesicle , biochemistry , pharmacology , biology

Salicylate and chlorpromazine exert differential effects on the chemokine release from mast cells. Since these drugs are amphiphilic and preferentially partitioned into the lipid bilayers of the plasma membranes, they would induce some morphological changes in mast cells and thus affect the process of exocytosis.

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