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Screening for Congenital Hypothyroidism: Comparison of Borderline Screening Cut-Off Points and the Effect on the Number of Children Treated with Levothyroxine
Author(s) -
Shirley Langham,
Peter C. Hindmarsh,
Steven Krywawych,
Catherine Peters
Publication year - 2013
Publication title -
european thyroid journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.23
H-Index - 10
eISSN - 2235-0802
pISSN - 2235-0640
DOI - 10.1159/000350039
Subject(s) - levothyroxine , medicine , newborn screening , pediatrics , congenital hypothyroidism , thyroid stimulating hormone , thyroid
The newborn screening programme for congenital hypothyroidism (CH) has led to the prevention of severe developmental delay associated with this condition. In the UK, thyroid-stimulating hormone (TSH) screening cut-off points have changed over time, in some instances prompted by changing methodological platforms. The use of borderline cut-off points varies throughout the country.

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