Monitoring of Platelet Activation in Platelet Concentrates Using Transmission Electron Microscopy | Zendy

Josef Neumüller | Zendy; Claudia Meißlitzer-Ruppitsch | Zendy; Adolf Ellinger | Zendy; Margit Pavelka | Zendy; Christof Jungbauer | Zendy; Renate Renz | Zendy; Gerda Leitner | Zendy; Thomas Wagner | Zendy

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Monitoring of Platelet Activation in Platelet Concentrates Using Transmission Electron Microscopy

Author(s) -

Josef Neumüller,

Claudia Meißlitzer-Ruppitsch,

Adolf Ellinger,

Margit Pavelka,

Christof Jungbauer,

Renate Renz,

Gerda Leitner,

Thomas Wagner

Publication year - 2013

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000350034

Subject(s) - platelet , apheresis , buffy coat , transmission electron microscopy , plateletpheresis , medicine , andrology , biomedical engineering , chemistry , surgery , immunology , materials science , nanotechnology

The quality of platelet concentrates (PC) is important for the in vivo recovery of thrombostasis in patients suffering from bleeding disorders and in tumor patients after chemotherapy. In this respect, activated platelets (PLT) cannot display their full functionality in the recipient and even can cause adverse effects. Therefore, we developed a transmission electron microscopy (TEM) method for quality assessment of PC.

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