WNT5A is a Key Regulator of the Epithelial-Mesenchymal Transition and Cancer Stem Cell Properties in Human Gastric Carcinoma Cells | Zendy

Maki Kanzawa | Zendy; Shuho Semba | Zendy; Shigeo Hara | Zendy; Tomoo Itoh | Zendy; Hiroshi Yokozaki | Zendy

Open Access

WNT5A is a Key Regulator of the Epithelial-Mesenchymal Transition and Cancer Stem Cell Properties in Human Gastric Carcinoma Cells

Author(s) -

Maki Kanzawa,

Shuho Semba,

Shigeo Hara,

Tomoo Itoh,

Hiroshi Yokozaki

Publication year - 2013

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000346843

Subject(s) - epithelial–mesenchymal transition , biology , cancer stem cell , gene knockdown , cancer research , cancer cell , signal transduction , microarray analysis techniques , wnt signaling pathway , mesenchymal stem cell , stem cell , cancer , microbiology and biotechnology , gene expression , cell culture , metastasis , gene , genetics

Direct interaction with cancer-associated fibroblasts triggers WNT5A expression in human gastric carcinoma (GC) cells. In this study, we performed gene transduction experiments to investigate the significance of WNT5A in the GC tumor microenvironment.

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