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Resistance to erythropoiesis-stimulating agent (ESA) is associated with mortality in hemodialysis (HD) patients. Time-dependent variability of ESA resistance has been not investigated adequately, although consistently high ESA resistance is expected to be a high risk for mortality. Our aim, therefore, was to investigate consistently high ESA resistance as an independent predictor of mortality in HD patients.

nephron. clinical practice

Time-Dependent Resistance to Erythropoiesis-Stimulating Agent and Mortality in Hemodialysis Patients in the Japan Dialysis Outcomes and Practice Patterns Study