Lung Stem and Progenitor Cells | Zendy

Karthikeyan Ardhanareeswaran | Zendy; Maria Mirotsou | Zendy

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Lung Stem and Progenitor Cells

Author(s) -

Karthikeyan Ardhanareeswaran,

Maria Mirotsou

Publication year - 2013

Publication title -

respiration

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.264

H-Index - 81

eISSN - 1423-0356

pISSN - 0025-7931

DOI - 10.1159/000346500

Subject(s) - progenitor cell , stem cell , lung , medicine , embryonic stem cell , endothelial stem cell , mesenchymal stem cell , regenerative medicine , stem cell therapy , adult stem cell , microbiology and biotechnology , immunology , pathology , biology , genetics , gene , in vitro

Over the past few years, new insights have been added to the study of stem cells in the adult lung. The exploration of endogenous lung progenitors as well as the study of exogenously delivered stem cell populations holds promise for advancing our understanding of the biology of lung repair mechanisms. Moreover, it opens new possibilities for the use of stem cell therapy for the development of regenerative medicine approaches for the treatment of lung disease. Here, we discuss the main types of lung epithelial progenitor populations; the potential of endothelial progenitors, mesenchymal stem cells and embryonic stem cells for lung therapy, as well as summarize the cellular mechanisms involved.

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