Open AccessPostmortem Brain Levels of Urate and Precursors in Parkinson's Disease and Related Disorders
Author(s) -
Nikolaus R. McFarland,
Thomas C. Burdett,
Cody A. Desjardins,
Matthew P. Frosch,
Michael A. Schwarzschild
Publication year - 2013
Publication title -
neurodegenerative diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.98
H-Index - 57
eISSN - 1660-2862
pISSN - 1660-2854
DOI - 10.1159/000346370
Subject(s) - dementia with lewy bodies , medicine , endocrinology , uric acid , alzheimer's disease , xanthine , parkinson's disease , dementia , disease , chemistry , biochemistry , enzyme
Increasing evidence suggests that urate may play an important role in neurodegenerative disease. In Parkinson's disease (PD) higher, but still normal, levels of blood and cerebrospinal fluid urate have been associated with a lower rate of disease progression.
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