Sublingual Immunotherapy for Experimental Allergic Conjunctivitis in a Murine Model Induced by Dermatophagoides farinae Allergen | Zendy

Li-lin Liu | Zendy; Dandan Guo | Zendy; Qiao-xia Liang | Zendy; Shengyong Ding | Zendy; Jing-ya Chen | Zendy; Bing Wu | Zendy; Qin Li | Zendy

Open Access

Sublingual Immunotherapy for Experimental Allergic Conjunctivitis in a Murine Model Induced by Dermatophagoides farinae Allergen

Author(s) -

Li-lin Liu,

Dandan Guo,

Qiao-xia Liang,

Shengyong Ding,

Jing-ya Chen,

Bing Wu,

Qin Li

Publication year - 2013

Publication title -

international archives of allergy and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.696

H-Index - 100

eISSN - 1423-0097

pISSN - 1018-2438

DOI - 10.1159/000346335

Subject(s) - immunoglobulin e , immunology , medicine , slit , allergic conjunctivitis , immunotherapy , allergy , immune system , cytokine , interleukin 4 , allergen , antibody , biology , genetics

Sublingual immunotherapy (SLIT) is a clinically effective treatment in allergic conjunctivitis (AC); however, the mechanism of the underlying pharmacodynamics remains unclear. Here, we investigate the efficacy and the mechanism of a sublingually administered Dermatophagoides farinae (Der f) vaccine in a murine AC model.

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