Optimal Dose Period for Indisetron Tablets for Preventing Chemotherapy-Induced Nausea and Vomiting with Modified FOLFOX6: A Randomized Pilot Study
Author(s) -
Hiroshi Nakatsumi,
Yoshito Komatsu,
Satoshi Yuki,
Susumu Sogabe,
Miki Tateyama,
Shuichi Muto,
Mineo Kudo,
Kanji Kato,
Takuto Miyagishima,
Minoru Uebayashi,
Takashi Meguro,
Koji Oba,
Masahiro Asaka
Publication year - 2012
Publication title -
chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.539
H-Index - 54
eISSN - 1421-9794
pISSN - 0009-3157
DOI - 10.1159/000345920
Subject(s) - nausea , vomiting , medicine , chemotherapy , randomized controlled trial , chemotherapy induced nausea and vomiting , anesthesia , pharmacology , surgery , antiemetic
Indisetron is a serotonin (5-hydroxytryptamine type 3) receptor antagonist that also antagonizes 5-hydroxytryptamine type 4 receptors. We designed a pilot study in order to explore the optimal dosing period for indisetron during modified FOLFOX6 (mFOLFOX6).
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