Open AccessReliable Determination of Fetal RhD Status by <b><i>RHD </i></b>Genotyping from Maternal Plasma
Author(s) -
Tadeja Dovč-Drnovšek,
Polona Klemenc,
Nataša Toplak,
Tanja Blejec,
Irena Bricl,
Primož Rožman
Publication year - 2013
Publication title -
transfusion medicine and hemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.971
H-Index - 39
eISSN - 1660-3818
pISSN - 1660-3796
DOI - 10.1159/000345682
Subject(s) - genotyping , fetus , medicine , pregnancy , prenatal diagnosis , genotype , obstetrics , biology , genetics , gene
Immunoprophylaxis with IgG anti-D is a standard prevention of hemolytic disease of the fetus and newborn. Fetal Rhesus D (RhD) blood group genotyping from maternal plasma of RhD-negative pregnant women allows targeted prophylaxis with IgG anti-D in RhD-positive pregnancies only. We set up a reliable protocol for prenatal RHD genotyping.
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