Chronic Evaluation of a Clinical System for Deep Brain Stimulation and Recording of Neural Network Activity | Zendy

Paul H. Stypulkowski | Zendy; Scott Stanslaski | Zendy; Timothy Denison | Zendy; Jonathon E. Giftakis | Zendy

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Chronic Evaluation of a Clinical System for Deep Brain Stimulation and Recording of Neural Network Activity

Author(s) -

Paul H. Stypulkowski,

Scott Stanslaski,

Timothy Denison,

Jonathon E. Giftakis

Publication year - 2013

Publication title -

stereotactic and functional neurosurgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.798

H-Index - 63

eISSN - 1423-0372

pISSN - 1011-6125

DOI - 10.1159/000345493

Subject(s) - deep brain stimulation , neuroscience , hippocampal formation , stimulation , neuromodulation , medicine , epilepsy , excitatory postsynaptic potential , inhibitory postsynaptic potential , psychology , parkinson's disease , disease

In conjunction with therapeutic stimulation, next-generation deep brain stimulation (DBS) devices may offer the ability to record and analyze neural signals, providing for unprecedented insight into DBS effects on neural networks. This work was conducted to evaluate an implantable, clinical-grade system that permits concurrent stimulation and recording using a large animal (ovine) model recently developed to study DBS for epilepsy.

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