Open AccessAn Efficient Method for Isolation of Hantaan Virus through Serial Passages in Suckling Mice
Author(s) -
J.-L. Li,
Jiaxin Ling,
L.-J. Chen,
Fenghuan Wei,
Fangyu Luo,
Y.-Y. Liu,
Hairong Xiong,
W. How,
Zhaoen Yang
Publication year - 2013
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000345444
Subject(s) - hantavirus , hantaan virus , virology , biology , virus , rodent , microbiology and biotechnology , ecology
Hantaan virus (HTNV) is one of the main etiologic agents for hemorrhagic fever with renal syndrome in China. However, it is very difficult to isolate the virus from its original host, which hampers the viral characterization. This study describes an efficient method for isolating HTNV in suckling mice.
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