Nitric Oxide Activates IL-6 Production and Expression in Human Renal Epithelial Cells | Zendy

Isak Demirel | Zendy; Ravi Vumma | Zendy; Camilla Mohlin | Zendy; Lovisa Svensson | Zendy; Susanne Säve | Zendy; Katarina Persson | Zendy

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Nitric Oxide Activates IL-6 Production and Expression in Human Renal Epithelial Cells

Author(s) -

Isak Demirel,

Ravi Vumma,

Camilla Mohlin,

Lovisa Svensson,

Susanne Säve,

Katarina Persson

Publication year - 2012

Publication title -

american journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 85

eISSN - 1421-9670

pISSN - 0250-8095

DOI - 10.1159/000345351

Subject(s) - messenger rna , nitric oxide , nitric oxide synthase , kidney , urinary system , microbiology and biotechnology , cytokine , medicine , endocrinology , biology , gene , biochemistry

Increased nitric oxide (NO) production or inducible form of NO synthase activity have been documented in patients suffering from urinary tract infection (UTI), but the role of NO in this infection is unclear. We investigated whether NO can affect the host response in human renal epithelial cells by modulating IL-6 production and mRNA expression.

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