Prognosis in Patients with Non-Small Cell Lung Cancer Who Received Erlotinib Treatment and Subsequent Dose Reduction due to Skin Rash
Author(s) -
Naoki Takashima,
Toshikiro Kimura,
Naohiro Watanabe,
Takumi Umemura,
Shinya Katsuno,
Keiko Arakawa,
Masahiro Fukatsu,
Naoto Nakamura,
Osamu Nishiyama,
Kensuke Kataoka,
Yasuhiro Kondoh,
Hiroyuki Taniguchi
Publication year - 2012
Publication title -
onkologie
Language(s) - English
Resource type - Journals
eISSN - 1423-0240
pISSN - 0378-584X
DOI - 10.1159/000345039
Subject(s) - erlotinib , rash , medicine , erlotinib hydrochloride , lung cancer , epidermal growth factor receptor , adverse effect , gastroenterology , dermatology , oncology , cancer
Severe skin rash as toxicity of erlotinib has been reported in relation to better response and survival. However, some patients require dose reduction due to skin toxicities, and their prognosis remains uncertain. We retrospectively evaluated the clinical course of non-small cell lung cancer patients receiving erlotinib at a reduced dose because of skin rash.
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