English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Results Characteristics of 82 patients are shown in table 1 . In 15 cases (18%), we observed a new WML in the zone distal to the old lacunar infarct. An example is given in figure 1 . One of these patients had a transient ischemic attack during follow-up, with clinical symptoms similar to the former lacunar stroke syndrome; none had deterioration of stroke symptoms with poor outcome or a recurrent stroke during follow-up.  Lacunar infarcts are presumed to be caused by occlusion of a single deep perforating artery [1] . White matter lesions (WMLs) might be caused by chronic hypoperfusion leading to ischemia or blood-brain barrier damage [2, 3] . In a follow-up MRI study in lacunar stroke patients, we observed a new WML in the zone adjacent to and just distal (in the vascular territory) from the old infarct in some of the cases. Subsequently, we reviewed all 2-year follow-up scans of our lacunar stroke patient cohort for this particular imaging feature. We describe this imaging feature and discuss a possible mechanism for these WMLs.

The Appearance of a New White Matter Lesion Adjacent to the Old Infarct in First-Ever Lacunar Stroke Patients: A Two-Year Follow-Up Study with MRI