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Histone H3 lysine 4 is trimethylated by the human Set1 complex, which regulates the activation of gene expression. The aim of this study was to identify whether the levels of histone H3 lysine 4 trimethylation (H3K4me3) and the recruitment of human Set1 complex at the promoter regions of lytic genes quantitatively change during reactivation from latent to lytic infection of Kaposi's sarcoma-association herpesvirus (KSHV).

intervirology

Alteration of Histone H3 Lysine 4 Trimethylation on Putative Lytic Gene Promoters by Human Set1 Complex during Reactivation of Kaposi’s Sarcoma-Associated Herpesvirus