Renoprotective Effects of Sildenafil in DOCA-Salt Hypertensive Rats | Zendy

Eun Hui Bae | Zendy; In Jin Kim | Zendy; Soo Yeon Joo | Zendy; Eun Young Kim | Zendy; Chang Seong Kim | Zendy; Joon Seok Choi | Zendy; Seong Kwon | Zendy; Suhn Hee Kim | Zendy; Jong Un Lee | Zendy; Soo Wan Kim | Zendy

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Renoprotective Effects of Sildenafil in DOCA-Salt Hypertensive Rats

Author(s) -

Eun Hui Bae,

In Jin Kim,

Soo Yeon Joo,

Eun Young Kim,

Chang Seong Kim,

Joon Seok Choi,

Seong Kwon,

Suhn Hee Kim,

Jong Un Lee,

Soo Wan Kim

Publication year - 2012

Publication title -

kidney and blood pressure research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.806

H-Index - 51

eISSN - 1423-0143

pISSN - 1420-4096

DOI - 10.1159/000343414

Subject(s) - sildenafil , medicine , pharmacology , endocrinology , chemistry

Sildenafil, the first selective phosphodiesterase-5 (PDE5) inhibitor to be widely used for treating erectile dysfunction, has been investigated with regard to its cardioand renoprotective effects in animal models. This study further investigated the renoprotective effects of sildenafil and their molecular mechanisms in deoxycorticosterone acetate (DOCA)-salt hypertensive (DSH) rats.

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