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The Enhanced Renin-Angiotensin-Aldosteron System Pharmacological Blockade - Which is the Best?
Author(s) -
Leszek Tylicki,
Sławomir Lizakowski,
Przemysław Rutkowski,
Marcin Renke,
Beata Sulikowska,
Zbigniew Heleniak,
Rafał Donderski,
Rafał Bednarski,
Milena Przybylska,
Jacek Manitius,
Piotr Rutkowski
Publication year - 2012
Publication title -
kidney and blood pressure research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.806
H-Index - 51
eISSN - 1423-0143
pISSN - 1420-4096
DOI - 10.1159/000343391
Subject(s) - telmisartan , medicine , albuminuria , urology , aliskiren , eplerenone , combination therapy , irbesartan , pharmacology , endocrinology , losartan , proteinuria , mineralocorticoid receptor , amlodipine , ramipril , lisinopril , blood pressure , renin–angiotensin system , aldosterone , angiotensin converting enzyme , kidney
Pharmacological inhibition of renin-angiotensin-aldosteron system (RAAS) may reduce proteinuria and the rate of chronic kidney disease progression. The aim was to compare the effects on albuminuria of the therapy with either: (i) telmisartan 80 mg and aliskiren 300 mg, (ii) telmisartan 80 mg and eplerenone 50 mg, (iii) telmisartan 160 mg as monotherapy.

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