Open AccessBlockage of Peripheral NPY Y1 and Y2 Receptors Modulates Barorefex Sensitivity of Diabetic Rats
Author(s) -
Jing Liu,
Ning Wang,
Fang Xie,
Lihua Sun,
Qingxin Chen,
Jian-Han Ye,
Benzhi Cai,
Baofeng Yang,
Jing Ai
Publication year - 2013
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000343379
Subject(s) - medicine , endocrinology , neuropeptide y receptor , hyperlipidemia , diabetes mellitus , chemistry , receptor , neuropeptide
Abnormal baroreceptor reflex sensitivity (BRS) and elevated plasma neuropeptide Y (NPY) are prevalent in diabetic patients. The present study was conducted to determine whether NPY Y1 receptor (Y1R) and NPY Y2 receptor (Y2R) contribute to the regulatin of BRS in diabetic rats.
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