Epigallocatechin Gallate Attenuated the Activation of Rat Cardiac Fibroblasts Induced by Angiotensin II via Regulating �-Arrestin1 | Zendy

Yongsheng Han | Zendy; Lei Lan | Zendy; Jun Chu | Zendy; Weiqiang Kang | Zendy; Zhiming Ge | Zendy

Open Access

Epigallocatechin Gallate Attenuated the Activation of Rat Cardiac Fibroblasts Induced by Angiotensin II via Regulating �-Arrestin1

Author(s) -

Yongsheng Han,

Lei Lan,

Jun Chu,

Weiqiang Kang,

Zhiming Ge

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000343371

Subject(s) - angiotensin ii , blot , endocrinology , medicine , chemistry , messenger rna , protein kinase c , small interfering rna , renin–angiotensin system , signal transduction , microbiology and biotechnology , receptor , biology , biochemistry , rna , gene , blood pressure

Angiotensin II (AngII) activated cardiac fibroblasts (CFs) predominantly through AngII subtype 1a receptor (AT1aR). This study was carried out to explore the potential inhibitory effects and mechanisms of epigallocatechin gallate (EGCG) on AngII induced rat CFs.

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