Comparison of GLUT1, GLUT2, GLUT4 and SGLT1 mRNA Expression in the Salivary Glands and Six Other Organs of Control, Streptozotocin-Induced and Goto-Kakizaki Diabetic Rats | Zendy

Cédric Jurysta | Zendy; Charles Nicaise | Zendy; Marie-Hélène Giroix | Zendy; Sibel Cetik | Zendy; Willy Malaisse | Zendy; Abdullah Sener | Zendy

Open Access

Comparison of GLUT1, GLUT2, GLUT4 and SGLT1 mRNA Expression in the Salivary Glands and Six Other Organs of Control, Streptozotocin-Induced and Goto-Kakizaki Diabetic Rats

Author(s) -

Cédric Jurysta,

Charles Nicaise,

Marie-Hélène Giroix,

Sibel Cetik,

Willy Malaisse,

Abdullah Sener

Publication year - 2013

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000343347

Subject(s) - glut2 , glut4 , glut1 , endocrinology , medicine , glucose transporter , streptozotocin , parotid gland , diabetes mellitus , glucose transporter type 1 , salivary gland , insulin , biology , immunohistochemistry , messenger rna , blot , pathology , biochemistry , gene

The expression and localization of several distinct glucose transporters (GLUT1, GLUT2, GLUT4, and SGLT1) was recently characterized in the parotid gland of normal rats by quantitative real-time PCR analysis, immunohistochemistry and Western blotting. The major aims of the present study was to compare the mRNA expression of these glucose transporters in both the parotid gland and submaxillary gland of control rats, streptozotocin-induced diabetic rats and hereditarily diabetic Goto-Kakizaki rats.

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