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Circulating fibrocytes (CFs) have been placed at the center of a number of fibrosing conditions. Recently, attention has been drawn to the non-anticoagulant activities of low molecular weight heparin (LH), especially its anti-fibrotic effects. The purpose of this study was to investigate the effects of LH on CFs differentiation and possible underlying mechanisms.

Low Molecular Weight Heparin Inhibits Circulating Fibrocytes Differentiation by Modulating Neuronal Nitric Oxide Synthase and TGF-�1/Smad Pathway