Human NRDRB1, an Alternatively Spliced Isoform of NADP(H)-Dependent Retinol Dehydrogenase/Reductase Enhanced Enzymatic Activity of Benzil | Zendy

Yinxia Yan | Zendy; Xuhong Song | Zendy; Gefei Liu | Zendy; Zhongjing Su | Zendy; Yongming Du | Zendy; Xuxia Sui | Zendy; Xiaolan Chang | Zendy; Dongyang Huang | Zendy

Open Access

Human NRDRB1, an Alternatively Spliced Isoform of NADP(H)-Dependent Retinol Dehydrogenase/Reductase Enhanced Enzymatic Activity of Benzil

Author(s) -

Yinxia Yan,

Xuhong Song,

Gefei Liu,

Zhongjing Su,

Yongming Du,

Xuxia Sui,

Xiaolan Chang,

Dongyang Huang

Publication year - 2012

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000343326

Subject(s) - enzyme , gene isoform , biochemistry , chemistry , dehydrogenase , benzil , reductase , gene , catalysis

Human NRDRB1, a 226 amino acid alternatively spliced isoform of the NADP(H)- dependent retinol dehydrogenase/reductase (NRDR), lacks the complete coding region of exon 3, but preserves all the important functional motifs for NRDR catalytic activity. Nevertheless, its tissue distribution and physiological function remain to be elucidated.

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