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Articular chondrocytes dwell in an environment that is continuously changing its osmolarity as a consequence of mechanical loading, yet their volume regulation capabilities (RVD) are not fully understood. This work aimed to determine the osmotic sensitivity of freshly isolated rat chondrocytes, their RVD capabilities and to study the properties of any anion currents associated.

cellular physiology and biochemistry

The Role of Swelling-Activated Chloride Currents (I<sub>CL,swell</sub>) in the Regulatory Volume Decrease Response of Freshly Dissociated Rat Articular Chondrocytes

The Role of Swelling-Activated Chloride Currents (ICL,swell) in the Regulatory Volume Decrease Response of Freshly Dissociated Rat Articular Chondrocytes

The Role of Swelling-Activated Chloride Currents (I_CL,swell) in the Regulatory Volume Decrease Response of Freshly Dissociated Rat Articular Chondrocytes