Radially Branched Deployment for More Efficient Cell Transplantation at the Scale of the Human Brain | Zendy

Matthew T. Silvestrini | Zendy; Dali Yin | Zendy; Valerie G. Coppes | Zendy; Preeti Mann | Zendy; Alastair J. Martin | Zendy; Paul Larson | Zendy; Philip A. Starr | Zendy; Nalin Gupta | Zendy; S. Scott Panter | Zendy; Tejal A. Desai | Zendy; Daniel A. Lim | Zendy

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Radially Branched Deployment for More Efficient Cell Transplantation at the Scale of the Human Brain

Author(s) -

Matthew T. Silvestrini,

Dali Yin,

Valerie G. Coppes,

Preeti Mann,

Alastair J. Martin,

Paul Larson,

Philip A. Starr,

Nalin Gupta,

S. Scott Panter,

Tejal A. Desai,

Daniel A. Lim

Publication year - 2013

Publication title -

stereotactic and functional neurosurgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.798

H-Index - 63

eISSN - 1423-0372

pISSN - 1011-6125

DOI - 10.1159/000343213

Subject(s) - cannula , transplantation , medicine , in vivo , neuroscience , surgery , biology , microbiology and biotechnology

In preclinical studies, cell transplantation into the brain has shown great promise for the treatment of a wide range of neurological diseases. However, the use of a straight cannula and syringe for cell delivery to the human brain does not approximate cell distribution achieved in animal studies. This technical deficiency may limit the successful clinical translation of cell transplantation.

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