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A Phase I Trial and in vitro Studies Combining ABT-751 with Carboplatin in Previously Treated Non-Small Cell Lung Cancer Patients
Author(s) -
Tian Ma,
Alexander D. Fuld,
James R. Rigas,
A. Hagey,
Gary Gordon,
Ethan Dmitrovsky,
Konstantin H. Dragnev
Publication year - 2012
Publication title -
chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.539
H-Index - 54
eISSN - 1421-9794
pISSN - 0009-3157
DOI - 10.1159/000343165
Subject(s) - carboplatin , medicine , lung cancer , neutropenia , cancer , gastroenterology , chemotherapy , pharmacology , cisplatin
ABT-751 is a novel antimitotic agent that exerted cytotoxic effects in preclinical studies. Carboplatin has efficacy in treating advanced non-small cell lung cancer (NSCLC) in combination with other drugs.

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