Allergen Sensitization Is Associated with Increased DNA Methylation in Older Men
Author(s) -
Joanne E. Sordillo,
Nancy E. Lange,
Letizia Tarantini,
Valentina Bollati,
Antonella Zanobetti,
David Sparrow,
Pantel Vokonas,
Joel Schwartz,
Andrea Baccarelli,
Dawn L. DeMeo,
Augusto A. Litonjua
Publication year - 2012
Publication title -
international archives of allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.696
H-Index - 100
eISSN - 1423-0097
pISSN - 1018-2438
DOI - 10.1159/000343004
Subject(s) - sensitization , immunology , dna methylation , allergen , medicine , dna , allergy , biology , genetics , gene , gene expression
Variation in epigenetic modifications, arising from either environmental exposures or internal physiological changes, can influence gene expression and may ultimately contribute to complex diseases such as asthma and allergies. We examined the association of asthma and allergic phenotypes with DNA methylation levels of retrotransposon-derived elements.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom