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Fighting Outbreaks with Bacterial Genomics: Case Review and Workflow Proposal
Author(s) -
Man Kit Cheung,
Hoi Shan Kwan
Publication year - 2012
Publication title -
public health genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 51
eISSN - 1662-8063
pISSN - 1662-4246
DOI - 10.1159/000342770
Subject(s) - outbreak , genome , context (archaeology) , bacterial genome size , whole genome sequencing , genomics , dna sequencing , workflow , biology , computational biology , genetics , gene , computer science , virology , database , paleontology
Disease outbreak investigation is a key aspect of public health. Whole-genome sequencing of bacterial pathogen based on new generation high-throughput sequencing technologies has facilitated outbreak investigations recently. Whilst the approach has become more affordable and accessible to research and clinical laboratories, a system for adequate and efficient analyses of genome data in the context of bacterial outbreak investigations is missing.

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