Immunohistochemical Analysis of Inflammatory Cells in Benign and Precancerous Lesions and Carcinoma of the Prostate | Zendy

Tomomi Fujii | Zendy; Kaoru Shimada | Zendy; Osamu Asai | Zendy; Nobumichi Tanaka | Zendy; Kiyohide Fujimoto | Zendy; Kazuyuki Hirao | Zendy; Noboru Konishi | Zendy

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Immunohistochemical Analysis of Inflammatory Cells in Benign and Precancerous Lesions and Carcinoma of the Prostate

Author(s) -

Tomomi Fujii,

Kaoru Shimada,

Osamu Asai,

Nobumichi Tanaka,

Kiyohide Fujimoto,

Kazuyuki Hirao,

Noboru Konishi

Publication year - 2013

Publication title -

pathobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.941

H-Index - 53

eISSN - 1423-0291

pISSN - 1015-2008

DOI - 10.1159/000342396

Subject(s) - prostate , cd68 , adenocarcinoma , pathology , hyperplasia , prostate cancer , intraepithelial neoplasia , immunohistochemistry , carcinogenesis , carcinoma , medicine , cancer

Inflammation is an important cause of tumorigenesis in various types of malignancy. Mediators derived from inflammatory cells are associated with cancer proliferation, angiogenesis, and DNA damage. In the present study, we immunohistochemically examined the infiltration patterns of inflammatory cells in benign glands including glandular hyperplasia, and in prostatic intraepithelial neoplasia and adenocarcinoma.

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