Open AccessHyaluronan, a Ready Choice to Fuel Regeneration: A Mini-Review
Author(s) -
Stephan Reitinger,
Günter Lepperdinger
Publication year - 2012
Publication title -
gerontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.397
H-Index - 94
eISSN - 1423-0003
pISSN - 0304-324X
DOI - 10.1159/000342200
Subject(s) - regeneration (biology) , regenerative medicine , transplantation , chemistry , microbiology and biotechnology , cell , biology , medicine , biochemistry
Hyaluronan (HA) is present in extracellular spaces and interstitia of many tissue types. As it is capable of binding high amounts of water, HA provides ideal conditions for cell migration and proliferation. Under conditions of cellular crowding, it also permits lineage-specific differentiation and thus promotes many aspects of healing and tissue remodeling.
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