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Fecal immunochemical test (FIT) is an integral component of most colorectal cancer (CRC) screening programs. However, little is known about clinical risk factors associated with advanced colorectal neoplasia (CRN) despite negative FIT results. The aim of this study was to determine the clinical predictors of advanced CRN despite negative FIT results.

First-Degree Relatives of Colorectal Cancer Patients Are Likely to Show Advanced Colorectal Neoplasia despite a Negative Fecal Immunochemical Test