Delayed Surgery for Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy: A Promising Method in Its Infancy | Zendy

Jiayuan Peng | Zendy; Jianzhong Di | Zendy; Yu Wang | Zendy

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Delayed Surgery for Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy: A Promising Method in Its Infancy

Author(s) -

Jiayuan Peng,

Jianzhong Di,

Yu Wang

Publication year - 2012

Publication title -

digestive surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.762

H-Index - 69

eISSN - 1421-9983

pISSN - 0253-4886

DOI - 10.1159/000341661

Subject(s) - medicine , colorectal cancer , chemoradiotherapy , neoadjuvant therapy , surgery , chemotherapy , cancer , oncology , general surgery , breast cancer

Neoadjuvant chemoradiotherapy (nCRT) is used to downstage locally advanced rectal cancer before surgery. Accumulating data suggest that tumor response to nCRT is time dependent. A delay between nCRT and surgery may increase the proportion of patients that achieve a favorable response. However, delayed surgery beyond 6-8 weeks may increase the technical difficulty, and the risks of surgical complications and recurrence or metastasis. This article briefly reviews the relevant literature to evaluate the efficiency and safety of delayed surgery.

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