Open AccessSphingosine Induces Apoptosis in MKN-28 Human Gastric Cancer Cells in an SDK-Dependent Manner
Author(s) -
Takeshi Kanno,
Takaaki Nishimoto,
Yumiko Fujita,
Akinobu Gotoh,
Takashi Nakano,
Tomoyuki Nishizaki
Publication year - 2012
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000341475
Subject(s) - sphingosine , protein kinase c , apoptosis , transfection , microbiology and biotechnology , sphingosine kinase 1 , cancer cell , biology , kinase , chemistry , cell culture , sphingosine 1 phosphate , biochemistry , cancer , receptor , genetics
Evidence has pointed to the role of sphingosine in cellular differentiation, cell growth, and apoptosis. The present study investigated sphingosine-induced apoptosis in human gastric cancer cells.
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