Vinpocetine Inhibits Oligodendroglial Precursor Cell Differentiation
Author(s) -
Klintsy J. Torres,
Peter Göttle,
David Kremer,
José FloresRivera,
Lucinda AguirreCruz,
Teresa Corona,
HansPeter Hartung,
Patrick Küry
Publication year - 2012
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000341451
Subject(s) - vinpocetine , rolipram , cilostazol , phosphodiesterase , microglia , pharmacology , multiple sclerosis , neuroprotection , cell , medicine , neuroscience , chemistry , biology , immunology , inflammation , biochemistry , enzyme , aspirin
In multiple sclerosis during periods of remission a limited degree of myelin repair can be observed mediated by oligodendroglial precursor cells. Phosphodiesterase inhibitors act as anti-inflammatory agents and might hold promise for future multiple sclerosis treatment.
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