A Mechanistic Study of the Effect of Doxorubicin/Adriamycin on the Estrogen Response in a Breast Cancer Model | Zendy

Jessica Pritchard | Zendy; Patrick M. Dillon | Zendy; Mark R. Conaway | Zendy; Corinne M. Silva | Zendy; Sarah J. Parsons | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

A Mechanistic Study of the Effect of Doxorubicin/Adriamycin on the Estrogen Response in a Breast Cancer Model

Author(s) -

Jessica Pritchard,

Patrick M. Dillon,

Mark R. Conaway,

Corinne M. Silva,

Sarah J. Parsons

Publication year - 2012

Publication title -

oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.987

H-Index - 98

eISSN - 1423-0232

pISSN - 0030-2414

DOI - 10.1159/000341394

Subject(s) - doxorubicin , estrogen , estrogen receptor , breast cancer , cancer research , estrogen receptor alpha , pharmacology , cancer cell , cell growth , medicine , cancer , endocrinology , chemotherapy , chemistry , biology , biochemistry

Estrogen treatment limits the cytotoxic effects of chemotherapy in estrogen receptor-positive (ER+) breast cancer cell lines, suggesting that estrogen pathway signaling may confer chemotherapeutic resistance. This study investigates the molecular responses of ER+ breast cancer cell lines to the chemotherapeutic agent, doxorubicin, in the presence or absence of estrogen.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research