Changes in Gene Expression Profile in Human Subcutaneous Adipose Tissue during Significant Weight Loss
Author(s) -
Céline Leyvraz,
Chantal Verdumo,
Michel Suter,
Alexandre Paroz,
JeanMarie Calmes,
Pedro MarquesVidal,
Vittorio Giusti
Publication year - 2012
Publication title -
obesity facts
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.398
H-Index - 45
eISSN - 1662-4033
pISSN - 1662-4025
DOI - 10.1159/000341137
Subject(s) - medicine , leptin , endocrinology , adipose tissue , weight loss , obesity , gene expression , gene , biology , biochemistry
To analyze the expression of peroxisome proliferator-activated receptor-γ1 and 2 (PPARγ1 and 2), 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1), and leptin in adipose tissue (AT) of obese women during weight loss following Roux-en-Y gastric bypass (RYGB) and to compare these levels with those obtained in AT of nonobese subjects.
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