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Symptomatic Intracranial Hemorrhage following Intravenous Thrombolysis for Acute Ischemic Stroke: A Critical Review of Case Definitions
Author(s) -
Raymond C.S. Seet,
Alejandro A. Rabinstein
Publication year - 2012
Publication title -
cerebrovascular diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 104
eISSN - 1421-9786
pISSN - 1015-9770
DOI - 10.1159/000339675
Subject(s) - medicine , thrombolysis , intracerebral hemorrhage , stroke (engine) , cohort , fibrinolytic agent , anesthesia , surgery , tissue plasminogen activator , glasgow coma scale , myocardial infarction , mechanical engineering , engineering
Symptomatic intracranial hemorrhage (SICH) is a devastating complication of intravenous thrombolysis treatment that is associated with high mortality. Clinical trials, stroke registries and cohort studies employ different case definitions to identify stroke patients with SICH following intravenous thrombolysis. We systematically reviewed the reported rates of SICH following intravenous thrombolysis and compared their consistency with mortality outcomes.

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