Open AccessA Random Change Point Model for Cognitive Decline in Alzheimer’s Disease and Mild Cognitive Impairment
Author(s) -
Lei Yu,
Patricia Boyle,
R. J. Wilson,
Eisuke Segawa,
Sue E. Leurgans,
Philip L. De Jager,
David A. Bennett
Publication year - 2012
Publication title -
neuroepidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.217
H-Index - 87
eISSN - 1423-0208
pISSN - 0251-5350
DOI - 10.1159/000339365
Subject(s) - cognitive decline , medicine , dementia , cognition , cohort , alzheimer's disease , gerontology , demography , disease , psychiatry , sociology
We present a random change point model to characterize decline in cognition among community-based elderly who developed Alzheimer's disease (AD) or amnestic mild cognitive impairment (MCI), and to examine how decline varies with age, sex, education, and APOE status.
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