Open AccessRole of Adherens Junction Proteins in Differential Herpes Simplex Virus Type 2 Infectivity in Communication-Competent and -Deficient Cell Lines
Author(s) -
Blair Miezeiewski,
Kerry McShane-Kay,
Richard I. Woodruff,
Gustave K.N. Mbuy,
Maureen Knabb
Publication year - 2012
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000339301
Subject(s) - adherens junction , infectivity , biology , cell culture , microbiology and biotechnology , hela , transfection , virology , mutant , herpes simplex virus , virus , cell , cadherin , gene , genetics
Gap junctional intercellular communication decreases with HSV-2 infection. To determine the importance of functional gap junctions for infectivity, we compared HSV-2 growth in communication-competent and -deficient cell lines.
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