Alveolar Macrophage Cathelicidin Deficiency in Severe Sarcoidosis
Author(s) -
Barbara P. Barna,
Daniel A. Culver,
Ali Kanchwala,
Ravinder J. Singh,
Isham Huizar,
Susamma Abraham,
Anagha Malur,
Irene Marshall,
Mani S. Kavuru,
Mary Jane Thomassen
Publication year - 2012
Publication title -
journal of innate immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.078
H-Index - 64
eISSN - 1662-8128
pISSN - 1662-811X
DOI - 10.1159/000339149
Subject(s) - cathelicidin , medicine , immunology , calcitriol receptor , alveolar macrophage , immune system , proinflammatory cytokine , tumor necrosis factor alpha , endocrinology , macrophage , vitamin d and neurology , inflammation , innate immune system , biology , in vitro , biochemistry
Dysfunctional immune responses characterize sarcoidosis, but the status of cathelicidin, a potent immunoregulatory and antimicrobial molecule, has not been established in clinical disease activity.
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