Open AccessNADPH Oxidase 2-derived Reactive Oxygen Species are Involved in Dysfunction and Apoptosis of Pancreatic ß-cells Induced by Low Density Lipoprotein
Author(s) -
Miao Li,
Lin Dou,
Juan Jiao,
Yonggang Lu,
Hanbang Guo,
Yong Man,
Shu Wang,
Jian Li
Publication year - 2012
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000339037
Subject(s) - endocrinology , medicine , nadph oxidase , apoptosis , reactive oxygen species , insulin , chemistry , pancreatic islets , apolipoprotein e , biology , islet , oxidative stress , biochemistry , disease
Increased levels of plasma cholesterol are a common feature of patient of type 2 diabetes. However, the links between elevated levels of low-density lipoprotein (LDL) and dysfunction of β-cells are still unclear.
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