Apolipoprotein A5 Gene Promoter Region<b><i>-1131T/C</i></b> Polymorphism Is Associated with Risk of Ischemic Stroke and Elevated Triglyceride Levels: A Meta-Analysis
Author(s) -
Yan Pi,
Lili Zhang,
Qingwu Yang,
BingHu Li,
Lu Guo,
Chuanqin Fang,
ChangYue Gao,
Jingzhou Wang,
Jing Xiang,
Jing-Cheng Li
Publication year - 2012
Publication title -
cerebrovascular diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.221
H-Index - 104
eISSN - 1421-9786
pISSN - 1015-9770
DOI - 10.1159/000338781
Subject(s) - medicine , odds ratio , confidence interval , subgroup analysis , triglyceride , gastroenterology , apolipoprotein b , genotype , ischemic stroke , endocrinology , bioinformatics , cholesterol , ischemia , genetics , gene , biology
The association between polymorphism -1131T/C in the promoter region of apolipoprotein A5 (APOA5) and ischemic stroke and plasma triglyceride (TG) levels remains controversial. To better clarify the association between APOA5-1131T/C and risk of ischemic stroke and plasma TG levels, we performed a meta-analysis to examine the allele and genotype of APOA5-1131T/C polymorphism in ischemic stroke cases and controls.
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