Surgical Trauma and Postoperative Immune Dysfunction | Zendy

P. Menges | Zendy; Wolfram Keßler | Zendy; C. Kloecker | Zendy; Martin Feuerherd | Zendy; Sophie Gaubert | Zendy; Stephan Diedrich | Zendy; Julia van der Linde | Zendy; A. Hegenbart | Zendy; A. Busemann | Zendy; Tobias Traeger | Zendy; Katharina Cziupka | Zendy; Claus-Dieter Heidecke | Zendy; Steffen Maier | Zendy

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Surgical Trauma and Postoperative Immune Dysfunction

Author(s) -

P. Menges,

Wolfram Keßler,

C. Kloecker,

Martin Feuerherd,

Sophie Gaubert,

Stephan Diedrich,

Julia van der Linde,

A. Hegenbart,

A. Busemann,

Tobias Traeger,

Katharina Cziupka,

Claus-Dieter Heidecke,

Steffen Maier

Publication year - 2012

Publication title -

european surgical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.658

H-Index - 46

eISSN - 1421-9921

pISSN - 0014-312X

DOI - 10.1159/000338196

Subject(s) - medicine , immune system , lymphocytopenia , sepsis , polytrauma , lymphocyte , immunology , surgery

In postoperative sepsis, mortality is increased due to the surgically induced immune dysfunction. Further causes of this traumatic effect on the immune system include burn injuries and polytrauma, as well as endogenous traumata like stroke. Several animal models have been defined to analyse the characteristics of trauma-induced immune suppression. This article will correlate our results from animal studies and clinical observations with the recent literature on postoperative immune suppression.

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