Effects of Glyceryl Glucoside on AQP3 Expression, Barrier Function and Hydration of Human Skin | Zendy

Ab SCHRADER | Zendy; Wilfried Siefken | Zendy; Thomas Kueper | Zendy; Ute Breitenbach | Zendy; C. Gatermann | Zendy; Gabi Sperling | Zendy; T. Biernoth | Zendy; C. Scherner | Zendy; Franz Stäb | Zendy; Horst Wenck | Zendy; KlausPeter Wittern | Zendy; Thomas Blatt | Zendy

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Effects of Glyceryl Glucoside on AQP3 Expression, Barrier Function and Hydration of Human Skin

Author(s) -

Ab SCHRADER,

Wilfried Siefken,

Thomas Kueper,

Ute Breitenbach,

C. Gatermann,

Gabi Sperling,

T. Biernoth,

C. Scherner,

Franz Stäb,

Horst Wenck,

KlausPeter Wittern,

Thomas Blatt

Publication year - 2012

Publication title -

skin pharmacology and physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.703

H-Index - 74

eISSN - 1660-5535

pISSN - 1660-5527

DOI - 10.1159/000338190

Subject(s) - aquaporin 3 , downregulation and upregulation , transepidermal water loss , aquaporin , epidermis (zoology) , chemistry , barrier function , in vitro , in vivo , human skin , messenger rna , glycerol , microbiology and biotechnology , biochemistry , andrology , biology , medicine , pathology , anatomy , gene , genetics , stratum corneum

Aquaporins (AQPs) present in the epidermis are essential hydration-regulating elements controlling cellular water and glycerol transport. In this study, the potential of glyceryl glucoside [GG; alpha-D-glucopyranosyl-alpha-(1->2)-glycerol], an enhanced glycerol derivative, to increase the expression of AQP3 in vitro and ex vivo was evaluated.

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